PDE7A 抗体
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北京 101111
Quick Overview for PDE7A 抗体 (ABIN7230562)
抗原
See all PDE7A 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-PDE7A Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of PDE7A protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human PDE7A protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- PDE7A (phosphodiesterase 7A (PDE7A))
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别名
- PDE7A
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背景
- High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, HCP1, TM22The protein encoded by PDE7A belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for PDE7A. PDE7A (Phosphodiesterase 7A) is a Protein Coding gene. Diseases associated with PDE7A include Chronic Lymphocytic Leukemia and Low Compliance Bladder. Among its related pathways are G alpha(s) signalling events and Ectoderm Differentiation.
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分子量
- 53kD
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基因ID
- 5150
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UniProt
- Q13946
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途径
- cAMP Metabolic Process
抗原
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