PDE4C 抗体 (AA 260-340)
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Quick Overview for PDE4C 抗体 (AA 260-340) (ABIN7216476)
抗原
See all PDE4C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 260-340
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原理
- Rabbit Anti-PDE4C Polyclonal Antibody
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特异性
- PDE4C Polyclonal Antibody detects endogenous levels of PDE4C protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human PDE4C at AA range: 260-340
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- PDE4C (phosphodiesterase 4C, CAMP-Specific (PDE4C))
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别名
- PDE4C
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背景
- PDE4C, DPDE1, cAMP-specific 3', 5'-cyclic phosphodiesterase 4C, DPDE1, PDE21Phosphodiesterase 4C encoded by PDE4C belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, phosphodiesterase 4C plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for PDE4C.
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分子量
- 80kD
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基因ID
- 5143
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UniProt
- Q08493
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途径
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process
抗原
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