PDE3A 抗体 (AA 250-330)
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Quick Overview for PDE3A 抗体 (AA 250-330) (ABIN7230556)
抗原
See all PDE3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 250-330
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原理
- PDE3A Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of PDE3A protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human PDE3A protein at AA range: 250-330
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))
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别名
- PDE3A
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背景
- Rabbit Anti-PDE3A Polyclonal Antibody,cGMP-inhibited 3',5'-cyclic phosphodiesterase A, Cyclic GMP-inhibited phosphodiesterase A, CGI-PDE A,PDE3A encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PDE3A.,PDE3A
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分子量
- observerd band 125kDa
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基因ID
- 5139
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UniProt
- Q14432
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途径
- cAMP Metabolic Process
抗原
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