PDE10A 抗体 (AA 40-120)
Quick Overview for PDE10A 抗体 (AA 40-120) (ABIN7219164)
抗原
See all PDE10A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-120
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原理
- PDE10A Polyclonal Antibody
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特异性
- PDE10A Polyclonal Antibody detects endogenous levels of PDE10A protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human PDE10A at AA range: 40-120
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PDE10A (phosphodiesterase 10A (PDE10A))
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别名
- PDE10A
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背景
- Rabbit Anti-PDE10A Polyclonal Antibody,PDE10A, cAMP and cAMP-inhibited cGMP 3', 5'-cyclic phosphodiesterase 10A,The phosphodiesterase 10A encoded by PDE10A belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for PDE10A.,cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
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分子量
- observerd band 75kDa
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基因ID
- 10846
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UniProt
- Q9Y233
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途径
- cAMP Metabolic Process
抗原
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