PREX1 抗体 (AA 340-420)
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Quick Overview for PREX1 抗体 (AA 340-420) (ABIN7230776)
抗原
See all PREX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 340-420
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原理
- PREX1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of PREX1 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human PREX1 protein at AA range: 340-420
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亚型
- IgG
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anti-Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1) (AA 1134-1163), (C-Term) antibody
PREX1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB31307 unconjugated
anti-Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1) (AA 1-44) antibodyPREX1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1) (Internal Region) antibodyVerified PREX1 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1) (Internal Region) antibodyPREX1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1) (AA 1133-1163), (C-Term) antibodyPREX1 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))
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别名
- PREX1
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背景
- Rabbit Anti-PREX1 Polyclonal Antibody,Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, P-Rex1, PtdIns(3,4,5)-dependent Rac exchanger 1,PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 1) is a Protein Coding gene. Diseases associated with PREX1 include Luminal Breast Carcinoma. Among its related pathways are p75 NTR receptor-mediated signalling and RET signaling. The protein encoded by PREX1 acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.,PREX1
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分子量
- observerd band 182kDa
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基因ID
- 57580
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UniProt
- Q8TCU6
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途径
- Regulation of Actin Filament Polymerization
抗原
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