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PIGA 抗体 (AA 410-490)

This 兔 多克隆 anti-PIGA antibody specifically detects PIGA in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7230638
发货至: 中国
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Quick Overview for PIGA 抗体 (AA 410-490) (ABIN7230638)

抗原

See all PIGA 抗体
PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))

适用

  • 37
  • 20
  • 18
  • 4
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 37
  • 1

克隆类型

  • 37
  • 1
多克隆

标记

  • 15
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PIGA antibody is un-conjugated

应用范围

  • 33
  • 13
  • 13
  • 10
  • 6
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 410-490

    原理

    PIGA Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of PIGA protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human PIGA protein at AA range: 410-490

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis, Class A (PIGA))

    别名

    PIGA

    背景

    Rabbit Anti-PIGA Polyclonal Antibody,Phosphatidylinositol N-acetylglucosaminyltransferase subunit A, GlcNAc-PI synthesis protein, Phosphatidylinositol-glycan biosynthesis class A protein, PIG-A,PIGA (Phosphatidylinositol Glycan Anchor Biosynthesis Class A) is a Protein Coding gene. Diseases associated with PIGA include Multiple Congenital Anomalies-Hypotonia-Seizures Syndrome 2 and Paroxysmal Nocturnal Hemoglobinuria, Somatic. Among its related pathways are Glycosylphosphatidylinositol (GPI)-anchor biosynthesis and Metabolism. PIGA encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12.,PIGA

    分子量

    observerd band 53kDa

    基因ID

    5277

    UniProt

    P37287

    途径

    Inositol Metabolic Process
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