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PEX19 抗体 (AA 190-270)

This 兔 多克隆 antibody specifically detects PEX19 in WB, ELISA 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7223858
发货至: 中国
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Quick Overview for PEX19 抗体 (AA 190-270) (ABIN7223858)

抗原

See all PEX19 抗体
PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

适用

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宿主

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克隆类型

  • 42
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多克隆

标记

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This PEX19 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 190-270

    原理

    Peroxin 19 Polyclonal Antibody

    特异性

    Peroxin 19 Polyclonal Antibody detects endogenous levels of Peroxin 19 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human Peroxin 19 at AA range: 190-270

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

    别名

    Peroxin 19

    背景

    Rabbit Anti-Peroxin 19 Polyclonal Antibody,PEX19, HK33, PXF, OK/SW-cl.22, Peroxisomal biogenesis factor 19, 33 kDa housekeeping protein, Peroxin-19, Peroxisomal farnesylated protein,PEX19 (peroxisomal biogenesis factor 19) is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in PEX19 are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.,Peroxisomal biogenesis factor 19

    分子量

    observerd band 33kDa

    基因ID

    5824

    UniProt

    P40855
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