PEX19 抗体 (AA 190-270)
Quick Overview for PEX19 抗体 (AA 190-270) (ABIN7223858)
抗原
See all PEX19 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 190-270
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原理
- Peroxin 19 Polyclonal Antibody
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特异性
- Peroxin 19 Polyclonal Antibody detects endogenous levels of Peroxin 19 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human Peroxin 19 at AA range: 190-270
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))
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别名
- Peroxin 19
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背景
- Rabbit Anti-Peroxin 19 Polyclonal Antibody,PEX19, HK33, PXF, OK/SW-cl.22, Peroxisomal biogenesis factor 19, 33 kDa housekeeping protein, Peroxin-19, Peroxisomal farnesylated protein,PEX19 (peroxisomal biogenesis factor 19) is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in PEX19 are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.,Peroxisomal biogenesis factor 19
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分子量
- observerd band 33kDa
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基因ID
- 5824
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UniProt
- P40855
抗原
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