PCM1 抗体 (AA 140-220)
Our Local Distributor
北京 101111
Quick Overview for PCM1 抗体 (AA 140-220) (ABIN7230526)
抗原
See all PCM1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 140-220
-
原理
- PCM1 Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of PCM1 protein
-
纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
-
免疫原
- Synthesized peptide derived from part region of human PCM1 protein at AA range: 140-220
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- PCM1 (Pericentriolar Material 1 (PCM1))
-
别名
- PCM1
-
背景
- Rabbit Anti-PCM1 Polyclonal Antibody,Pericentriolar material 1 protein, PCM-1, hPCM-1,PCM1 (Pericentriolar Material 1) is a Protein Coding gene. Diseases associated with PCM1 include Differentiated Thyroid Carcinoma and Atypical Chronic Myeloid Leukemia. Among its related pathways are DNA Damage and Regulation of PLK1 Activity at G2/M Transition. The protein encoded by PCM1 is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for PCM1.,PCM1
-
分子量
- observerd band 222kDa
-
基因ID
- 5108
-
UniProt
- Q15154
-
途径
- Stem Cell Maintenance, M Phase, Maintenance of Protein Location
抗原
-