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PCM1 抗体 (AA 140-220)

The 兔 多克隆 anti-PCM1 antibody (ABIN7230526) specifically detects PCM1 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7230526
发货至: 中国
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Quick Overview for PCM1 抗体 (AA 140-220) (ABIN7230526)

抗原

See all PCM1 抗体
PCM1 (Pericentriolar Material 1 (PCM1))

适用

  • 24
  • 6
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 24
  • 2

克隆类型

  • 26
多克隆

标记

  • 20
  • 2
  • 1
  • 1
  • 1
  • 1
This PCM1 antibody is un-conjugated

应用范围

  • 25
  • 15
  • 12
  • 10
  • 7
  • 4
  • 2
  • 2
Western Blotting (WB), ELISA
  • 抗原表位

    • 9
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 140-220

    原理

    PCM1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of PCM1 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human PCM1 protein at AA range: 140-220

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PCM1 (Pericentriolar Material 1 (PCM1))

    别名

    PCM1

    背景

    Rabbit Anti-PCM1 Polyclonal Antibody,Pericentriolar material 1 protein, PCM-1, hPCM-1,PCM1 (Pericentriolar Material 1) is a Protein Coding gene. Diseases associated with PCM1 include Differentiated Thyroid Carcinoma and Atypical Chronic Myeloid Leukemia. Among its related pathways are DNA Damage and Regulation of PLK1 Activity at G2/M Transition. The protein encoded by PCM1 is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for PCM1.,PCM1

    分子量

    observerd band 222kDa

    基因ID

    5108

    UniProt

    Q15154

    途径

    Stem Cell Maintenance, M Phase, Maintenance of Protein Location
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