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PAX3 and PAX7 Binding Protein 1 (PAXBP1) 抗体

This 兔 多克隆 antibody specifically detects PAX3 and PAX7 Binding Protein 1 in WB 和 ELISA. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7228626
发货至: 中国
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Quick Overview for PAX3 and PAX7 Binding Protein 1 (PAXBP1) 抗体 (ABIN7228626)

抗原

See all PAX3 and PAX7 Binding Protein 1 (PAXBP1) 抗体
PAX3 and PAX7 Binding Protein 1 (PAXBP1)

适用

  • 24
  • 10
  • 8
  • 8
  • 7
  • 7
  • 6
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
人, 小鼠

宿主

  • 23
  • 1

克隆类型

  • 24
多克隆

标记

  • 19
  • 1
  • 1
  • 1
  • 1
  • 1
非结合性

应用范围

  • 15
  • 10
  • 6
  • 2
Western Blotting (WB), ELISA
  • 原理

    Rabbit Anti-GCFC1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of GCFC1 protein

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human GCFC1 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    PAX3 and PAX7 Binding Protein 1 (PAXBP1)

    别名

    GCFC1

    背景

    PAX3- and PAX7-binding protein 1, GC-rich sequence DNA-binding factor 1PAXBP1 encodes the PAX3 And PAX7 Binding Protein 1 that may bind to GC-rich DNA sequences, which suggests its involvement in the regulation of transcription. Alternative splicing of this gene results in multiple transcript variants. Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of Lys-4 of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20 (By similarity).

    分子量

    100kD

    基因ID

    94104

    UniProt

    Q9Y5B6
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