PAX3 and PAX7 Binding Protein 1 (PAXBP1) 抗体
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Quick Overview for PAX3 and PAX7 Binding Protein 1 (PAXBP1) 抗体 (ABIN7228626)
抗原
See all PAX3 and PAX7 Binding Protein 1 (PAXBP1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- GCFC1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of GCFC1 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human GCFC1 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PAX3 and PAX7 Binding Protein 1 (PAXBP1)
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别名
- GCFC1
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背景
- Rabbit Anti-GCFC1 Polyclonal Antibody,PAX3- and PAX7-binding protein 1, GC-rich sequence DNA-binding factor 1,PAXBP1 encodes the PAX3 And PAX7 Binding Protein 1 that may bind to GC-rich DNA sequences, which suggests its involvement in the regulation of transcription. Alternative splicing of this gene results in multiple transcript variants. Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of Lys-4 of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20 (By similarity).,GCFC1
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分子量
- observerd band 100kDa
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基因ID
- 94104
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UniProt
- Q9Y5B6
抗原
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