PTH1R 抗体 (AA 1268-1341)
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Quick Overview for PTH1R 抗体 (AA 1268-1341) (ABIN7227082)
抗原
See all PTH1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1268-1341
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原理
- Rabbit Anti-Parathyroid hormone/parathyroid hormone-related peptide receptor Polyclonal Antibody
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特异性
- The antibody detects endogenous Parathyroid hormone/parathyroid hormone-related peptide receptor.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthetic peptide from human protein at AA range: 1268-1341
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:500-200,ELISA 1:10000-20000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
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别名
- Parathyroid hormone/parathyroid hormone-related peptide receptor
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背景
- Parathyroid hormone/parathyroid hormone-related peptide receptor, PTH/PTHrP type I receptor, PTH/PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptorThe protein encoded by PTH1R (parathyroid hormone 1 receptor) is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for PTH1R.
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分子量
- 66kD
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基因ID
- 5745
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UniProt
- Q03431
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途径
- Regulation of Carbohydrate Metabolic Process
抗原
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