PSPC1 抗体 (AA 10-90)
Quick Overview for PSPC1 抗体 (AA 10-90) (ABIN7230818)
抗原
See all PSPC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-90
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原理
- PSPC1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of PSPC1 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human PSPC1 protein at AA range: 10-90
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PSPC1 (Paraspeckle Component 1 (PSPC1))
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别名
- PSPC1
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背景
- Rabbit Anti-PSPC1 Polyclonal Antibody,Paraspeckle component 1, Paraspeckle protein 1,PSPC1 (Paraspeckle Component 1) is a Protein Coding gene. Diseases associated with PSPC1 include Eec Syndrome and Rapp-Hodgkin Syndrome. Among its related pathways are Circadian rythm related genes. PSPC1 encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by PSPC1 is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of PSPC1 results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified.,PSPC1
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分子量
- observerd band 57kDa
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基因ID
- 55269
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UniProt
- Q8WXF1
抗原
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