Pan Myristoylation 抗体
The 兔 多克隆 anti-Pan Myristoylation antibody is suitable to detect Pan Myristoylation in samples from Various Species. It has been validated for ELISA 和 WB.
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产品编号 ABIN7226980
发货至:
中国
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中国
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北京 101111
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Quick Overview for Pan Myristoylation 抗体 (ABIN7226980)
抗原
Pan Myristoylation
适用
Various Species
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB)
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原理
- Rabbit Anti-Pan myristoylation Polyclonal Antibody
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特异性
- The antibody detects endogenous myristoylated protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthetic myristoylated peptide
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Pan Myristoylation
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背景
- Pan3 (PAB-dependent poly(A)-specific ribonuclease subunit 3) is a 741 amino acid cytoplasmic protein belonging to the protein kinase superfamily. Containing a protein kinase domain, Pan3 is a component of the Pan nuclease complex and recruits polyadenylate-binding protein, which in turn stimulates Pan2 nuclease activity. It is suggested that Pan3 may have a functional role in cytoplasmic mRNA decay. Pan3 exists as three isoforms produced by alternative splicing and the gene encoding Pan3 is located on human chromosome 13. Chromosome 13 houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4 % of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
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分子量
- 130kD,80kD,35kD
抗原
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