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PAKbeta (pSer154) 抗体

This anti-PAKbeta antibody is a 兔 多克隆 antibody detecting PAKbeta in ELISA, WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7222928
发货至: 中国
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Quick Overview for PAKbeta (pSer154) 抗体 (ABIN7222928)

抗原

PAKbeta

适用

人, 小鼠, 大鼠

宿主

  • 3

克隆类型

  • 3
多克隆

标记

  • 3
非结合性

应用范围

  • 3
  • 3
  • 2
  • 1
ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 1
    • 1
    • 1
    pSer154

    原理

    PAKβ (phospho Ser154) Polyclonal Antibody

    特异性

    Phospho-PAKβ (S154) Polyclonal Antibody detects endogenous levels of PAKβ protein only when phosphorylated at S154.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human PAKbeta Phospho-Ser154

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PAKbeta

    背景

    Rabbit Anti-PAKβ (phospho Ser154) Polyclonal Antibody,PAK3, OPHN3, Serine/threonine-protein kinase PAK 3, Beta-PAK, Oligophrenin-3, p21-activated kinase 3, PAK-3,The protein encoded by PAK3 is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like P21, CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in PAK3 are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified.,serine threonine-protein kinase PAK 3

    分子量

    observerd band 72kDa

    基因ID

    5063

    UniProt

    O75914
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