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PAKalpha/beta/gamma 抗体

This anti-PAKalpha/beta/gamma antibody is a 兔 多克隆 antibody detecting PAKalpha/beta/gamma in ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7222906
发货至: 中国

Quick Overview for PAKalpha/beta/gamma 抗体 (ABIN7222906)

抗原

PAKalpha/beta/gamma

适用

人, 小鼠, 大鼠

宿主

  • 7

克隆类型

  • 7
多克隆

标记

  • 7
This PAKalpha/beta/gamma antibody is un-conjugated

应用范围

  • 7
  • 6
  • 4
  • 3
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 原理

    PAKα/β/γ Polyclonal Antibody

    特异性

    PAKα/β/γ Polyclonal Antibody detects endogenous levels of PAKα/β/γ protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human PAKalpha/beta/gamma around the non-phosphorylation site of S144/141/139

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PAKalpha/beta/gamma

    背景

    Rabbit Anti-PAKα/β/γ Polyclonal Antibody,PAK1, Serine/threonine-protein kinase PAK 1, Alpha-PAK, p21-activated kinase 1, PAK-1, p65-PAK, PAK2, Serine/threonine-protein kinase PAK 2, Gamma-PAK, PAK65, S6/H4 kinase, p21-activated kinase 2, PAK-2, p58, PAK3, OPHN3, Serine/threonine-p,PAK1 encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,serine threonine-protein kinase PAK 1

    基因ID

    5058, 5062, 5063
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