PAK5/6 抗体
This 兔 多克隆 anti-not_set antibody specifically detects not_set in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7223710
发货至:
中国
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中国
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北京 101111
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Quick Overview for PAK5/6 抗体 (ABIN7223710)
抗原
PAK5/6
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB), ELISA
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原理
- PAK5/6 Polyclonal Antibody
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特异性
- PAK5/6 Polyclonal Antibody detects endogenous levels of PAK5/6 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human PAK5/6 around the non-phosphorylation site of S602/S560
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亚型
- IgG
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anti-PAK5/6 (Ser1197) antibody
适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PAK5/6 (AA 566-615), (pSer602) antibody适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PAK5/6
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背景
- Rabbit Anti-PAK5/6 Polyclonal Antibody,PAK7, KIAA1264, PAK5, Serine/threonine-protein kinase PAK 7, p21-activated kinase 5, PAK-5, p21-activated kinase 7, PAK-7, PAK6, PAK5, Serine/threonine-protein kinase PAK 6, PAK-5, p21-activated kinase 6, PAK-6,The protein encoded by PAK5 (p21 (RAC1) activated kinase 5) is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.,serine threonine-protein kinase PAK 6
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分子量
- observerd band 75kDa
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基因ID
- 57144, 56924
抗原
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