PHOX2B 抗体 (AA 140-220)
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Quick Overview for PHOX2B 抗体 (AA 140-220) (ABIN7230626)
抗原
See all PHOX2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 140-220
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原理
- PHX2B Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of PHX2B protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human PHX2B protein at AA range: 140-220
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亚型
- IgG
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anti-Paired-Like Homeobox 2b (PHOX2B) (AA 104-130) antibody
PHOX2B 适用: 小鼠 WB, IF 宿主: 兔 Polyclonal RB28842 unconjugated
anti-Paired-Like Homeobox 2b (PHOX2B) (AA 104-130) antibodyPHOX2B 适用: 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Paired-Like Homeobox 2b (PHOX2B) antibodyPHOX2B 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paired-Like Homeobox 2b (PHOX2B) (AA 1-90) antibodyPHOX2B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Paired-Like Homeobox 2b (PHOX2B) antibodyPHOX2B 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Paired-Like Homeobox 2b (PHOX2B) (Internal Region) antibodyPHOX2B 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Paired-Like Homeobox 2b (PHOX2B) (N-Term) antibodyPHOX2B 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PHOX2B (Paired-Like Homeobox 2b (PHOX2B))
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别名
- PHX2B
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背景
- Rabbit Anti-PHX2B Polyclonal Antibody,Paired mesoderm homeobox protein 2B, Neuroblastoma Phox, NBPhox, PHOX2B homeodomain protein, Paired-like homeobox 2B,PHOX2B (Paired Like Homeobox 2b) is a Protein Coding gene. Diseases associated with PHOX2B include Central Hypoventilation Syndrome, Congenital and Neuroblastoma 2. Among its related pathways are Neural Crest Differentiation and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The DNA-associated protein encoded by PHOX2B is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. PHOX2B product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.,PHX2B
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分子量
- observerd band 34kDa
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基因ID
- 8929
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UniProt
- Q99453
抗原
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