PAX5 抗体 (AA 1-80)
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Quick Overview for PAX5 抗体 (AA 1-80) (ABIN7216458)
抗原
See all PAX5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-80
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原理
- Pax-5 Polyclonal Antibody
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特异性
- Pax-5 Polyclonal Antibody detects endogenous levels of Pax-5 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human Pax-5 at AA range: 1-80
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亚型
- IgG
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anti-Paired Box 5 (PAX5) (AA 192-301) antibody
PAX5 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 8F9 unconjugated
anti-Paired Box 5 (PAX5) (AA 235-382) antibodyPAX5 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal PAX5-3735 unconjugated
anti-Paired Box 5 (PAX5) (AA 235-382) antibodyPAX5 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 7D3 unconjugated
anti-Paired Box 5 (PAX5) (N-Term) antibodyVerified PAX5 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Paired Box 5 (PAX5) (AA 235-382) antibodyPAX5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A7 unconjugated
anti-Paired Box 5 (PAX5) (AA 178-207) antibodyPAX5 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 5 (PAX5) (AA 217-282) antibodyPAX5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 5 (PAX5) (AA 362-391) antibodyPAX5 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 5 (PAX5) (N-Term) antibodyPAX5 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 5 (PAX5) (AA 192-302) antibodyPAX5 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 8F9 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PAX5 (Paired Box 5 (PAX5))
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别名
- Pax-5
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背景
- Rabbit Anti-Pax-5 Polyclonal Antibody,PAX5, Paired box protein Pax-5, B-cell-specific transcription factor, BSAP,PAX5 encodes a member of the paired box (PAX) family of transcription factors. The central feature of PAX5 family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of PAX5 are thought to contribute to neoplastic transformation. PAX5 encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the paired box 5 may also play a role in neural development and spermatogenesis. PAX5 is located at 9p13, which is involved in t(9,14)(p13,q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of PAX5 contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms.,Paired box protein Pax-5
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分子量
- observerd band 40kDa
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基因ID
- 5079
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UniProt
- Q02548
抗原
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