P57 (acLys278) 抗体
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北京 101111
Quick Overview for P57 (acLys278) 抗体 (ABIN7212628)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- acLys278
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原理
- p57 (Acetyl Lys278) Polyclonal Antibody
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特异性
- Acetyl-p57 (K278) Polyclonal Antibody detects endogenous levels of p57 protein only when acetylated at K278.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human p57 around the acetylation site of K278
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亚型
- IgG
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anti-P57 (Ser24) antibody
适用: 人, 小鼠, 大鼠 IHC (p), WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P57 (acLys278) antibody适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-P57 antibody适用: 人, 小鼠 IHC (p), WB, IF, FACS 宿主: 小鼠 Monoclonal KP10 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- P57
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背景
- Rabbit Anti-p57 (Acetyl Lys278) Polyclonal Antibody,CDKN1C, KIP2, Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2,CDKN1C is imprinted, with preferential expression of the maternal allele. Cyclin dependent kinase inhibitor 1C is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in CDKN1C are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that CDKN1C is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for CDKN1C.,Cyclin-dependent kinase inhibitor 1C
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分子量
- observerd band 33kDa
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基因ID
- 1028
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UniProt
- P49918
抗原
-
