MAPK8IP1 抗体 (AA 425-524)
Quick Overview for MAPK8IP1 抗体 (AA 425-524) (ABIN716441)
抗原
See all MAPK8IP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 425-524
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交叉反应
- 人, 大鼠
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预测反应
- Mouse,Dog,Cow,Sheep,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human JIP1/MAPK8IP1
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) antibody
MAPK8IP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 470-498), (C-Term) antibodyMAPK8IP1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB23000 unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (Tyr466) antibodyMAPK8IP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 69-118) antibodyMAPK8IP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) antibodyMAPK8IP1 适用: 人 WB, IHC, FACS, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (pThr103) antibodyMAPK8IP1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 265-279) antibodyVerified MAPK8IP1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (pThr103) antibodyMAPK8IP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 470-498) antibodyMAPK8IP1 适用: 人 WB, IF, IHC, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) (AA 69-118), (pThr103) antibodyMAPK8IP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))
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别名
- Mapk8ip1
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背景
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Synonyms: IB1, JIP1, JIP-1, PRKM8IP, C-Jun-amino-terminal kinase-interacting protein 1, JNK-interacting protein 1, Islet-brain 1, IB-1, JNK MAP kinase scaffold protein 1, Mitogen-activated protein kinase 8-interacting protein 1, MAPK8IP1
Background: The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Required for JNK activation in response to excitotoxic stress. Cytoplasmic MAPK8IP1 causes inhibition of JNK-regulated activity by retaining JNK in the cytoplasm and inhibiting JNK phosphorylation of c-Jun. May also participate in ApoER2-specific reelin signaling. Directly, or indirectly, regulates GLUT2 gene expression and beta-cell function. Appears to have a role in cell signaling in mature and developing nerve terminals. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (By similarity). Functions as an anti-apoptotic protein and whose level seems to influence the beta-cell death or survival response.
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基因ID
- 9479
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UniProt
- Q9UQF2
抗原
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