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P-Cadherin 抗体 (AA 30-110)

This anti-P-Cadherin antibody is a 兔 多克隆 antibody detecting P-Cadherin in WB, ELISA 和 IHC (p). Suitable for 人.
产品编号 ABIN7218844
发货至: 中国

Quick Overview for P-Cadherin 抗体 (AA 30-110) (ABIN7218844)

抗原

See all P-Cadherin (CDH3) 抗体
P-Cadherin (CDH3)

适用

  • 120
  • 51
  • 9
  • 4
  • 4
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  • 3
  • 1
  • 1
  • 1

宿主

  • 95
  • 30
  • 5
  • 2

克隆类型

  • 95
  • 35
  • 1
多克隆

标记

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  • 12
  • 11
  • 5
  • 5
  • 4
  • 2
  • 2
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  • 2
  • 1
  • 1
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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This P-Cadherin antibody is un-conjugated

应用范围

  • 95
  • 49
  • 40
  • 37
  • 23
  • 15
  • 13
  • 13
  • 13
  • 11
  • 5
  • 3
  • 2
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  • 1
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  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
    • 9
    • 8
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-110

    原理

    P-cadherin Polyclonal Antibody

    特异性

    P-cadherin Polyclonal Antibody detects endogenous levels of P-cadherin protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the N-terminal region of human P-cadherin at AA range: 30-110

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    P-Cadherin (CDH3)

    别名

    P-cadherin

    背景

    Rabbit Anti-P-cadherin Polyclonal Antibody,CDH3, CDHP, Cadherin-3, Placental cadherin, P-cadherin,Placental Cadherin (P-Cadherin or PCAD) is a member of the cadherin family of cell adhesion molecules. Cadherins are calcium-dependent transmembrane proteins, which bind to one another in a homophilic manner. On their cytoplasmic side, they associate with the three catenins, alpha, beta, and gamma (plakoglobin). This association links the cadherin protein to the cytoskeleton. Without association with the catenins, the cadherins are non-adhesive. Cadherins play a role in development, specifically in tissue formation. They may also help to maintain tissue architecture in the adult. P-Cadherin is a classical cadherin molecule. Classical cadherins consist of a large extracellular domain which contains DXD and DXNDN repeats responsible for mediating calcium-dependent adhesion, a single-pass transmembrane domain, and a short carboxy-terminal cytoplasmic domain responsible for interacting with the catenins. Constitutive P-Cadherin expression is found in the epidermis, mesothelium, corneal epithelium, and uterine decidua. Mouse P-Cadherin is an 822 amino acid (aa) protein with a 27 aa signal sequence and a 795 aa propeptide. The mature protein begins at aa 100 and has a 542 aa extracellular region, a 27 aa transmembrane region, and a 153 aa cytoplasmic region.,Cadherin-3

    分子量

    observerd band 86kDa

    基因ID

    1001

    UniProt

    P22223
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