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OMG 抗体 (AA 260-340)

This 兔 多克隆 anti-OMG antibody specifically detects OMG in ELISA, WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7216318
发货至: 中国
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Quick Overview for OMG 抗体 (AA 260-340) (ABIN7216318)

抗原

See all OMG 抗体
OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

适用

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宿主

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克隆类型

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多克隆

标记

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This OMG antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 260-340

    原理

    OMG Polyclonal Antibody

    特异性

    OMG Polyclonal Antibody detects endogenous levels of OMG protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human OMG at AA range: 260-340

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

    别名

    OMG

    背景

    Rabbit Anti-OMG Polyclonal Antibody,OMG, OMGP, Oligodendrocyte-myelin glycoprotein,Oligodendrocyte myelin glycoprotein (OMG, OMgp) is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes that influences the development of the adult central nervous system (CNS). OMG inhibits neurite outgrowth through its interaction with the Nogo receptor. This function requires its leucine-rich repeat domain, a highly-conserved region in OMG that influences cell proliferation, formation and maintenance of myelin sheaths. OMG inhibits neurite outgrowth from rat cerebellar granule and hippocampal cells, from dorsal root ganglion explants in which growth cone collapse was observed, from rat retinal ganglion neurons, and from NG108 and PC-12 cells.,Oligodendrocyte-myelin glycoprotein

    分子量

    observerd band 48kDa

    基因ID

    4974

    UniProt

    P23515

    途径

    Neurotrophin Signaling Pathway, Regulation of Cell Size
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