OMG 抗体 (AA 260-340)
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北京 101111
Quick Overview for OMG 抗体 (AA 260-340) (ABIN7216318)
抗原
See all OMG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 260-340
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原理
- OMG Polyclonal Antibody
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特异性
- OMG Polyclonal Antibody detects endogenous levels of OMG protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human OMG at AA range: 260-340
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- OMG (Oligodendrocyte Myelin Glycoprotein (OMG))
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别名
- OMG
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背景
- Rabbit Anti-OMG Polyclonal Antibody,OMG, OMGP, Oligodendrocyte-myelin glycoprotein,Oligodendrocyte myelin glycoprotein (OMG, OMgp) is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes that influences the development of the adult central nervous system (CNS). OMG inhibits neurite outgrowth through its interaction with the Nogo receptor. This function requires its leucine-rich repeat domain, a highly-conserved region in OMG that influences cell proliferation, formation and maintenance of myelin sheaths. OMG inhibits neurite outgrowth from rat cerebellar granule and hippocampal cells, from dorsal root ganglion explants in which growth cone collapse was observed, from rat retinal ganglion neurons, and from NG108 and PC-12 cells.,Oligodendrocyte-myelin glycoprotein
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分子量
- observerd band 48kDa
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基因ID
- 4974
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UniProt
- P23515
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途径
- Neurotrophin Signaling Pathway, Regulation of Cell Size
抗原
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