OCRL 抗体 (Internal Region)
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北京 101111
Quick Overview for OCRL 抗体 (Internal Region) (ABIN7216158)
抗原
See all OCRL 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- OCRL Polyclonal Antibody
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特异性
- OCRL Polyclonal Antibody detects endogenous levels of OCRL protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human OCRL
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))
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别名
- OCRL
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背景
- Rabbit Anti-OCRL Polyclonal Antibody,OCRL, INPP5F, OCRL1, Inositol polyphosphate 5-phosphatase OCRL-1, Lowe oculocerebrorenal syndrome protein,OCRL encodes an inositol polyphosphate 5-phosphatase. OCRL, inositol polyphosphate-5-phosphatase is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. OCRL, inositol polyphosphate-5-phosphatase may also play a role in primary cilium formation. Mutations in OCRL cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.,Inositol polyphosphate 5-phosphatase OCRL-1
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分子量
- observerd band 104kDa
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基因ID
- 4952
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UniProt
- Q01968
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途径
- Inositol Metabolic Process
抗原
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