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NARF 抗体 (AA 230-310)

This 兔 多克隆 anti-NARF antibody specifically detects NARF in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7221022
发货至: 中国
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Quick Overview for NARF 抗体 (AA 230-310) (ABIN7221022)

抗原

See all NARF 抗体
NARF (Nuclear Prelamin A Recognition Factor (NARF))

适用

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宿主

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克隆类型

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  • 1
多克隆

标记

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This NARF antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 230-310

    原理

    NARF Polyclonal Antibody

    特异性

    NARF Polyclonal Antibody detects endogenous levels of NARF protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human NARF at AA range: 230-310

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    NARF (Nuclear Prelamin A Recognition Factor (NARF))

    别名

    NARF

    背景

    Rabbit Anti-NARF Polyclonal Antibody,NARF, Nuclear prelamin A recognition factor, Iron-only hydrogenase-like protein 2, IOP2,Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The nuclear prelamin A recognition factor encoded by NARF binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. The encoded protein is located in the nucleus, where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene, including one with a novel exon that is generated by RNA editing.,Nuclear prelamin A recognition factor

    分子量

    observerd band 51kDa

    基因ID

    26502

    UniProt

    Q9UHQ1
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