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NRARP 抗体

This anti-NRARP antibody is a 兔 多克隆 antibody detecting NRARP in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7230124
发货至: 中国

Quick Overview for NRARP 抗体 (ABIN7230124)

抗原

See all NRARP 抗体
NRARP (NOTCH-Regulated Ankyrin Repeat Protein (NRARP))

适用

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人, 小鼠

宿主

  • 33
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克隆类型

  • 35
多克隆

标记

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This NRARP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 原理

    NRARP Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of NRARP protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human NRARP protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    NRARP (NOTCH-Regulated Ankyrin Repeat Protein (NRARP))

    别名

    NRARP

    背景

    Rabbit Anti-NRARP Polyclonal Antibody,Notch-regulated ankyrin repeat-containing protein,NRARP (NOTCH Regulated Ankyrin Repeat Protein) is a Protein Coding gene. Among its related pathways are Notch signaling pathway (KEGG). Downstream effector of Notch signaling. Involved in the regulation of liver cancer cells self-renewal. Involved in angiogenesis acting downstream of Notch at branch points to regulate vascular density. Proposed to integrate endothelial Notch and Wnt signaling to control stalk cell proliferation and to stablilize new endothelial connections during angiogenesis. During somitogenesis involved in maintenance of proper somite segmentation and proper numbers of somites and vertebrae. Required for proper anterior-posterior somite patterning. Proposed to function in a negative feedback loop to destabilize Notch 1 intracellular domain (NICD) and downregulate the Notch signal, preventing expansion of the Notch signal into the anterior somite domain (By similarity).,NRARP

    分子量

    observerd band 12kDa

    基因ID

    441478

    UniProt

    Q7Z6K4
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