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NMDA epsilon 1/2 (pTyr1246), (pTyr1252) 抗体

This 兔 多克隆 antibody specifically detects NMDA epsilon 1/2 in ELISA, IF 和 IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7221330
发货至: 中国
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Quick Overview for NMDA epsilon 1/2 (pTyr1246), (pTyr1252) 抗体 (ABIN7221330)

抗原

NMDA epsilon 1/2

适用

人, 小鼠, 大鼠

宿主

  • 3

克隆类型

  • 3
多克隆

标记

  • 3
非结合性

应用范围

  • 3
  • 3
  • 2
  • 1
ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 1
    • 1
    • 1
    pTyr1246, pTyr1252

    原理

    NMDAε1/2 (phospho Tyr1246/1252) Polyclonal Antibody

    特异性

    Phospho-NMDAε1/2 (Y1246/1252) Polyclonal Antibody detects endogenous levels of NMDAε1/2 protein only when phosphorylated at Y1246/1252.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human NMDAepsilon1/2 Phospho-Tyr1246/1252

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    NMDA epsilon 1/2

    别名

    NMDAepsilon1/2

    背景

    Rabbit Anti-NMDAε1/2 (phospho Tyr1246/1252) Polyclonal Antibody,GRIN2A, NMDAR2A, Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, hNR2A, GRIN2B, NMDAR2B, Glutamate [NMDA] receptor subunit epsilon-2, N-methyl D-aspartate receptor subtype 2B, NMDAR2B, N,GRIN2A encodes a member of the glutamate-gated ion channel protein family. The glutamate ionotropic receptor NMDA type subunit 2A is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.,Glutamate [NMDA] receptor subunit epsilon-1

    基因ID

    2903, 2904
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