NLRP2 抗体 (AA 620-700)
Our Local Distributor
北京 101111
Quick Overview for NLRP2 抗体 (AA 620-700) (ABIN7229898)
抗原
See all NLRP2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 620-700
-
原理
- NALP2 Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of NALP2 protein
-
纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
-
免疫原
- Synthesized peptide derived from part region of human NALP2 protein at AA range: 620-700
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))
-
别名
- NALP2
-
背景
- Rabbit Anti-NALP2 Polyclonal Antibody,Nucleotide-binding site protein 1, PYRIN domain and NACHT domain-containing protein 1, PYRIN-containing APAF1-like protein 2,NLRP2 is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms.,NALP2
-
分子量
- observerd band 116kDa
-
基因ID
- 55655
-
UniProt
- Q9NX02
-
途径
- Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
-