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NLRP2 抗体 (AA 620-700)

This 兔 多克隆 anti-NLRP2 antibody specifically detects NLRP2 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7229898
发货至: 中国
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Quick Overview for NLRP2 抗体 (AA 620-700) (ABIN7229898)

抗原

See all NLRP2 抗体
NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

适用

  • 33
  • 9
  • 5
  • 1
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宿主

  • 26
  • 5
  • 2
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克隆类型

  • 30
  • 4
多克隆

标记

  • 34
This NLRP2 antibody is un-conjugated

应用范围

  • 31
  • 11
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  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 620-700

    原理

    NALP2 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of NALP2 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human NALP2 protein at AA range: 620-700

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

    别名

    NALP2

    背景

    Rabbit Anti-NALP2 Polyclonal Antibody,Nucleotide-binding site protein 1, PYRIN domain and NACHT domain-containing protein 1, PYRIN-containing APAF1-like protein 2,NLRP2 is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). Members of this gene family are thought to be important regulators of immune responses. This gene product interacts with components of the IkB kinase (IKK) complex, and can regulate both caspase-1 and NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells) activity. The pyrin domain is necessary and sufficient for suppression of NF-kB activity. An allelic variant (rs147585490) has been found that is incapable of blocking the transcriptional activity of NF-kB. Alternative splicing results in multiple transcript variants encoding different isoforms.,NALP2

    分子量

    observerd band 116kDa

    基因ID

    55655

    UniProt

    Q9NX02

    途径

    Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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