NEK3 抗体
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北京 101111
Quick Overview for NEK3 抗体 (ABIN7229960)
抗原
See all NEK3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-NEK3 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of NEK3 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human NEK3 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- NEK3 (NIMA related kinase 3 (NEK3))
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别名
- NEK3
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背景
- Serine/threonine-protein kinase Nek3, HSPK 36, Never in mitosis A-related kinase 3, NimA-related protein kinase 3NEK3 encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. NIMA Related Kinase 3 differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm. The kinase is activated by prolactin stimulation, leading to phosphorylation of VAV2 guanine nucleotide exchange factor, paxillin, and activation of the RAC1 GTPase. Multiple transcript variants encoding different isoforms have been found for this gene.
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分子量
- 55kD
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基因ID
- 4752
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UniProt
- P51956
抗原
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