NSG2 抗体 (AA 10-90)
Our Local Distributor
北京 101111
Quick Overview for NSG2 抗体 (AA 10-90) (ABIN7223076)
抗原
See all NSG2 (HMP19) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 10-90
-
原理
- HMP19 Polyclonal Antibody
-
特异性
- HMP19 Polyclonal Antibody detects endogenous levels of HMP19 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the Internal region of human HMP19 at AA range: 10-90
-
亚型
- IgG
-
-
anti-Neuron-Specific Protein Family Member 2 (HMP19) (C-Term) antibody
Verified HMP19 适用: 小鼠, 大鼠 ELISA, WB, ICC 宿主: 山羊 Polyclonal unconjugated
anti-Neuron-Specific Protein Family Member 2 (HMP19) (Center) antibodyHMP19 适用: 人, Cow, 猴 IHC, WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- NSG2 (HMP19) (Neuron-Specific Protein Family Member 2 (HMP19))
-
别名
- HMP19
-
背景
- Rabbit Anti-HMP19 Polyclonal Antibody,NSG2, Neuron-specific protein family member 2, Protein p19, Hmp19,The chondroitin sulfate proteoglycan NG2 is a type I membrane protein expressed by subpopulations of glia including oligodendroglial precursor cells and a variety of tumor cells. Normal precursor cells and malignant tumor cells migrate and proliferate, but there is evidence that cells may not be able to engage in both activities at the same time. However, NG2 is involved in promoting both proliferation and motility. The extracellular domain of NG2 sequesters growth factors and binds to both growth factor receptors and extracellular matrix ligands such as fibronectin, collagens and laminin. The cytoplasmic domain is involved in activating Rac, Cdc42 and p130 Cas. PKCα phosphorylates NG2 at Thr2256, triggering the redistribution of NG2 from apical microprocesses to lamellipodia accompanied by enhanced cell motility. ERK phosphorylates NG2 at Thr2314, stimulating cell proliferation.,Neuron-specific protein family member 2
-
分子量
- observerd band 19kDa
-
基因ID
- 51617
-
UniProt
- Q9Y328
抗原
-
