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Merlin 抗体 (pSer10)

The 兔 多克隆 anti-Merlin antibody is suitable to detect Merlin in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA 和 IHC (p).
产品编号 ABIN7222712
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Merlin 抗体 (pSer10) (ABIN7222712)

抗原

See all Merlin (NF2) 抗体
Merlin (NF2) (Neurofibromin 2 (NF2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Merlin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    pSer10

    原理

    NF2 (phospho Ser10) Polyclonal Antibody

    特异性

    Phospho-NF2 (S10) Polyclonal Antibody detects endogenous levels of NF2 protein only when phosphorylated at S10.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human NF2 Phospho-Ser10

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Merlin (NF2) (Neurofibromin 2 (NF2))

    别名

    NF2

    背景

    Rabbit Anti-NF2 (phospho Ser10) Polyclonal Antibody,NF2, SCH, Merlin, Moesin-ezrin-radixin-like protein, Neurofibromin-2, Schwannomerlin, Schwannomin,NF2 encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development, in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.,Merlin

    分子量

    observerd band 65kDa

    基因ID

    4771

    UniProt

    P35240

    途径

    Cell-Cell Junction Organization
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