NUB1 抗体 (AA 540-620)
Our Local Distributor
北京 101111
Quick Overview for NUB1 抗体 (AA 540-620) (ABIN7216142)
抗原
See all NUB1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 540-620
-
原理
- NUB1 Polyclonal Antibody
-
特异性
- NUB1 Polyclonal Antibody detects endogenous levels of NUB1 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the C-terminal region of human NUB1 at AA range: 540-620
-
亚型
- IgG
-
-
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 1-326) antibody
NUB1 适用: 人, 猴, 大鼠, 犬 WB, IHC, IHC (p), IF, FACS 宿主: 小鼠 Monoclonal 4H2 unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) antibodyNUB1 适用: 人, 小鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 1-326) antibodyNUB1 适用: 人 WB, IHC, IHC (p), FACS 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (C-Term) antibodyNUB1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 87-117), (N-Term) antibodyNUB1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2874 unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) antibodyNUB1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB15825 unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 1-601) antibodyNUB1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (C-Term) antibodyNUB1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) (AA 513-542), (C-Term) antibodyNUB1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2875 unconjugated
anti-Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1) antibodyNUB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- NUB1 (Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))
-
别名
- NUB1
-
背景
- Rabbit Anti-NUB1 Polyclonal Antibody,NUB1, NYREN18, NEDD8 µLtimate buster 1, Negative regulator of ubiquitin-like proteins 1, Renal carcinoma antigen NY-REN-18,NUB1 encodes a protein that functions as a negative regulator of NEDD8, a ubiquitin-like protein that conjugates with cullin family members in order to regulate vital biological events. Negative regulator of ubiquitin like proteins 1 encoded by NUB1 regulates the NEDD8 conjugation system post-transcriptionally by recruiting NEDD8 and its conjugates to the proteasome for degradation. Negative regulator of ubiquitin like proteins 1 interacts with the product of the AIPL1 gene, which is associated with Leber congenital amaurosis, an inherited retinopathy, and mutations in that gene can abolish interaction with negative regulator of ubiquitin like proteins 1, which may contribute to the pathogenesis. Negative regulator of ubiquitin like proteins 1 is also known to accumulate in Lewy bodies in Parkinson's disease and dementia with Lewy bodies, and in glial cytoplasmic inclusions in multiple system atrophy, with this abnormal accumulation being specific to alpha-synucleinopathy lesions. Alternative splicing of NUB1 results in multiple transcript variants.,NEDD8 µLtimate buster 1
-
分子量
- observerd band 70kDa
-
基因ID
- 51667
-
UniProt
- Q9Y5A7
抗原
-
