NDFIP2 抗体
Quick Overview for NDFIP2 抗体 (ABIN7229980)
抗原
See all NDFIP2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- NFIP2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of NFIP2 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human NFIP2 protein
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亚型
- IgG
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anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (Internal Region) antibody
NDFIP2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (AA 1-242) antibodyNDFIP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (AA 152-201) antibodyNDFIP2 适用: 人, 小鼠, Cow, 犬, 马, 大鼠, 斑马鱼, 豚鼠, Pig, Bat, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (AA 1-242) antibodyNDFIP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (AA 251-300) antibodyNDFIP2 适用: 人, 小鼠, Cow, 犬, 马, 大鼠, 斑马鱼, Pig, 兔, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (Middle Region) antibodyNDFIP2 适用: 人, 小鼠, Cow, 犬, 马, 大鼠, 斑马鱼, 豚鼠, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Nedd4 Family Interacting Protein 2 (NDFIP2) (N-Term) antibodyNDFIP2 适用: 人, 小鼠, Cow, 犬, 马, 大鼠, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- NDFIP2 (Nedd4 Family Interacting Protein 2 (NDFIP2))
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别名
- NFIP2
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背景
- Rabbit Anti-NFIP2 Polyclonal Antibody,NEDD4 family-interacting protein 2, NEDD4 WW domain-binding protein 5A, Putative MAPK-activating protein PM04/PM05/PM06/PM07, Putative NF-kappa-B-activating protein 413,NDFIP2 (Nedd4 Family Interacting Protein 2) is a Protein Coding gene. Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes. Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. Negatively regulates KCNH2 potassium channel activity by decreasing its cell-surface expression and interfering with channel maturation through recruitment of NEDD4L to the Golgi apparatus and multivesicular body where it mediates KCNH2 degradation. May modulate EGFR signaling. Together with NDFIP1, limits the cytokine signaling and expansion of effector Th2 T-cells by promoting degradation of JAK1, probably by ITCH- and NEDD4L-mediated ubiquitination.,NFIP2
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分子量
- observerd band 36kDa
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基因ID
- 54602
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UniProt
- Q9NV92
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途径
- Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome
抗原
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