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NCKIPSD 抗体

The 兔 多克隆 anti-NCKIPSD antibody (ABIN7231502) specifically detects NCKIPSD in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7231502
发货至: 中国
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Quick Overview for NCKIPSD 抗体 (ABIN7231502)

抗原

See all NCKIPSD 抗体
NCKIPSD (NCK Interacting Protein with SH3 Domain (NCKIPSD))

适用

  • 18
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人, 小鼠

宿主

  • 13
  • 5

克隆类型

  • 15
  • 3
多克隆

标记

  • 18
This NCKIPSD antibody is un-conjugated

应用范围

  • 14
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Western Blotting (WB), ELISA
  • 原理

    Rabbit Anti-SPN90 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of SPN90 protein

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthesized peptide derived from part region of human SPN90 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    NCKIPSD (NCK Interacting Protein with SH3 Domain (NCKIPSD))

    别名

    SPN90

    背景

    NCK-interacting protein with SH3 domain, 54 kDa VacA-interacting protein, 54 kDa vimentin-interacting protein, VIP54, 90 kDa SH3 protein interacting with Nck, AF3p21, Dia-interacting protein 1, DIP-1, Diaphanous protein-interacting protein, SH3 adapter protein SPIN90, WASP-interacting SH3-domain protein, WISH, Wiskott-Aldrich syndrome protein-interacting proteinThe protein encoded by NCKIPSD (NCK Interacting Protein With SH3 Domain) is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. NCKIPSD is involved in therapy-related leukemia by a chromosomal translocation t(3,11)(p21,q23) that involves NCKIPSD and the myeloid/lymphoid leukemia gene. Alternative splicing results in multiple transcript variants of NCKIPSD.

    分子量

    79kD

    基因ID

    51517

    UniProt

    Q9NZQ3

    途径

    Protein targeting to Nucleus
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