NCKIPSD 抗体
Quick Overview for NCKIPSD 抗体 (ABIN7231502)
抗原
See all NCKIPSD 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- SPN90 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of SPN90 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human SPN90 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- NCKIPSD (NCK Interacting Protein with SH3 Domain (NCKIPSD))
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别名
- SPN90
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背景
- Rabbit Anti-SPN90 Polyclonal Antibody,NCK-interacting protein with SH3 domain, 54 kDa VacA-interacting protein, 54 kDa vimentin-interacting protein, VIP54, 90 kDa SH3 protein interacting with Nck, AF3p21, Dia-interacting protein 1, DIP-1, Diaphanous protein-interacting protein, SH3 adapter protein SPIN90, WASP-interacting SH3-domain protein, WISH, Wiskott-Aldrich syndrome protein-interacting protein,The protein encoded by NCKIPSD (NCK Interacting Protein With SH3 Domain) is localized exclusively in the cell nucleus. It plays a role in signal transduction, and may function in the maintenance of sarcomeres and in the assembly of myofibrils into sarcomeres. It also plays an important role in stress fiber formation. NCKIPSD is involved in therapy-related leukemia by a chromosomal translocation t(3,11)(p21,q23) that involves NCKIPSD and the myeloid/lymphoid leukemia gene. Alternative splicing results in multiple transcript variants of NCKIPSD.,SPN90
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分子量
- observerd band 79kDa
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基因ID
- 51517
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UniProt
- Q9NZQ3
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途径
- Protein targeting to Nucleus
抗原
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