N/H/K-Ras (AA 10-90) 抗体
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北京 101111
Quick Overview for N/H/K-Ras (AA 10-90) 抗体 (ABIN7206804)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-90
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原理
- N/H/K-Ras Polyclonal Antibody
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特异性
- N/H/K-Ras Polyclonal Antibody detects endogenous levels of N/H/K-Ras protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human N/H/K-Ras at AA range: 10-90
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亚型
- IgG
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anti-N/H/K-Ras (N-Term) antibody
适用: 小鼠, 大鼠, 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-N/H/K-Ras antibody适用: 小鼠, 大鼠, 人 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-N/H/K-Ras antibody适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- N/H/K-Ras
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背景
- Rabbit Anti-N/H/K-Ras Polyclonal Antibody,NRAS, HRAS1, GTPase NRas, Transforming protein N-Ras, HRAS, HRAS1, GTPase HRas, H-Ras-1, Ha-Ras, Transforming protein p21, c-H-ras, p21ras, KRAS, KRAS2, RASK2, GTPase KRas, K-Ras 2, Ki-Ras, c-K-ras, c-Ki-ras,HRAS belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. GTPase Hras undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene.,GTPase Nras
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基因ID
- 3265, 3845, 4893
抗原
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