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MYL12B 抗体 (pSer18)

This 兔 多克隆 anti-MYL12B antibody specifically detects MYL12B in WB, ELISA, IF 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7221772
发货至: 中国
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Quick Overview for MYL12B 抗体 (pSer18) (ABIN7221772)

抗原

See all MYL12B 抗体
MYL12B (Myosin, Light Chain 12B, Regulatory (MYL12B))

适用

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  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 53
  • 5

克隆类型

  • 41
  • 16
多克隆

标记

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  • 1
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This MYL12B antibody is un-conjugated

应用范围

  • 41
  • 20
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer18

    原理

    MRLC2 (phospho Ser18) Polyclonal Antibody

    特异性

    Phospho-MRLC2 (S18) Polyclonal Antibody detects endogenous levels of MRLC2 protein only when phosphorylated at S18.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human MRLC2 Phospho-Ser18

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    MYL12B (Myosin, Light Chain 12B, Regulatory (MYL12B))

    别名

    MRLC2

    背景

    Rabbit Anti-MRLC2 (phospho Ser18) Polyclonal Antibody,MYL9, MLC2, MRLC1, MYRL2, Myosin regulatory light polypeptide 9, 20 kDa myosin light chain, LC20, MLC-2C, Myosin RLC, Myosin regulatory light chain 2, smooth muscle isoform, Myosin regulatory light chain 9, Myosin regulatory light chain MRL,Myosin is a highly conserved, ubiquitously expressed protein that interacts with Actin to generate the force for cellular movements. Conventional myosins are hexameric proteins consisting of two heavy chain subunits, a pair of non-phosphorylatable light chain subunits and a pair of phosphorylatable light chain subunits. Three general classes of myosin have been cloned: smooth muscle myosins, striated muscle myosins and non-muscle myosins. Myosin regulatory light chains, including MYL12A (also known as MRLC3 or MLCB), MYL12B (also known as MRLC2) and MYL9 (also known as LC20, MLC2, MRLC1 or MYRL2), regulate contraction in smooth muscle and non-muscle cells via phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases the Actin-activated myosin ATPase activity, thereby regulating the contractile activity. Myosin light chain is also located in striated skeletal muscle, where its function remains undefined.,Myosin regulatory light polypeptide 9

    分子量

    observerd band 18kDa

    基因ID

    3566

    UniProt

    P24844

    途径

    Feeding Behaviour
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