Myosin VIIA 抗体 (AA 830-910)
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Quick Overview for Myosin VIIA 抗体 (AA 830-910) (ABIN7229866)
抗原
See all Myosin VIIA (MYO7A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 830-910
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原理
- Rabbit Anti-MYO7A Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of MYO7A protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human MYO7A protein at AA range: 830-910
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Myosin VIIA (MYO7A)
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别名
- MYO7A
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背景
- Unconventional myosin-VIIaMYO7A (Myosin VIIA) is a Protein Coding gene. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Actin Nucleation by ARP-WASP Complex. MYO7A is a member of the myosin gene family. Myosins are mechanochemical proteins characterized by the presence of a motor domain, an actin-binding domain, a neck domain that interacts with other proteins, and a tail domain that serves as an anchor. MYO7A encodes an unconventional myosin with a very short tail. Defects in MYO7A are associated with the mouse shaker-1 phenotype and the human Usher syndrome 1B which are characterized by deafness, reduced vestibular function, and (in human) retinal degeneration. Alternative splicing results in multiple transcript variants.
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分子量
- 243kD
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基因ID
- 4647
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UniProt
- Q13402
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途径
- Sensory Perception of Sound
抗原
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