Myosin VI 抗体 (AA 40-120)
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Quick Overview for Myosin VI 抗体 (AA 40-120) (ABIN7217696)
抗原
See all Myosin VI (MYO6) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-120
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原理
- Rabbit Anti-Myosin VI Polyclonal Antibody
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特异性
- Myosin VI Polyclonal Antibody detects endogenous levels of Myosin VI protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the N-terminal region of human Myosin VI at AA range: 40-120
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:5000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Myosin VI (MYO6)
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别名
- Myosin VI
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背景
- MYO6, KIAA0389, Unconventional myosin-VI, Unconventional myosin-6MYO6 encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The unconventional myosin-VI consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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分子量
- 149kD
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基因ID
- 4646
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UniProt
- Q9UM54
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途径
- Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization
抗原
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