MPRIP 抗体 (Internal Region)
Quick Overview for MPRIP 抗体 (Internal Region) (ABIN7216892)
抗原
See all MPRIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- M-RIP Polyclonal Antibody
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特异性
- M-RIP Polyclonal Antibody detects endogenous levels of M-RIP protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human M-RIP
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MPRIP (Myosin Phosphatase rho Interacting Protein (MPRIP))
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别名
- M-RIP
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背景
- Rabbit Anti-M-RIP Polyclonal Antibody,MPRIP, KIAA0864, MRIP, RHOIP3, Myosin phosphatase Rho-interacting protein, M-RIP, Rho-interacting protein 3, RIP3, p116Rip,MPRIP (Myosin Phosphatase Rho Interacting Protein) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include actin binding. Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.,Myosin phosphatase Rho-interacting protein
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分子量
- observerd band 115kDa
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基因ID
- 23164
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UniProt
- Q6WCQ1
抗原
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