MNDA 抗体 (AA 350-430)
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Quick Overview for MNDA 抗体 (AA 350-430) (ABIN7222516)
抗原
See all MNDA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 350-430
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原理
- MNDA Polyclonal Antibody
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特异性
- MNDA Polyclonal Antibody detects endogenous levels of MNDA protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human MNDA at AA range: 350-430
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MNDA (Myeloid Cell Nuclear Differentiation Antigen (MNDA))
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别名
- MNDA
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背景
- Rabbit Anti-MNDA Polyclonal Antibody,MNDA, Myeloid cell nuclear differentiation antigen,The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.,Myeloid cell nuclear differentiation antigen
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分子量
- observerd band 46kDa
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基因ID
- 4332
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UniProt
- P41218
抗原
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