MAX 抗体 (pSer2)
Quick Overview for MAX 抗体 (pSer2) (ABIN7222374)
抗原
See all MAX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer2
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原理
- Max (phospho Ser2) Polyclonal Antibody
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特异性
- Phospho-Max (S2) Polyclonal Antibody detects endogenous levels of Max protein only when phosphorylated at S2.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human Max Phospho-Ser2
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MAX (MYC Associated Factor X (MAX))
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别名
- Max
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背景
- Rabbit Anti-Max (phospho Ser2) Polyclonal Antibody,MAX, BHLHD4, Protein max, Class D basic helix-loop-helix protein 4, bHLHd4, Myc-associated factor X,The protein encoded by MAX is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.,Protein max
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基因ID
- 4149
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UniProt
- P61244
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途径
- Mitotic G1-G1/S Phases
抗原
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