MUC4 抗体 (AA 1970-2050)
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Quick Overview for MUC4 抗体 (AA 1970-2050) (ABIN7229790)
抗原
See all MUC4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1970-2050
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原理
- MUC4 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of MUC4 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human MUC4 protein at AA range: 1970-2050
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MUC4 (Mucin 4, Cell Surface Associated (MUC4))
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别名
- MUC4
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背景
- Rabbit Anti-MUC4 Polyclonal Antibody,Mucin-4, MUC-4, Ascites sialoglycoprotein, ASGP, Pancreatic adenocarcinoma mucin, Testis mucin, Tracheobronchial mucin,MUC4 (Mucin 4, Cell Surface Associated) is a Protein Coding gene. Among its related pathways are O-linked glycosylation and HIV Life Cycle. The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. MUC4 encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of MUC4 have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. MUC4 contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats.,MUC4
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分子量
- observerd band 238kDa
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基因ID
- 4585
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UniProt
- Q99102
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途径
- Regulation of Leukocyte Mediated Immunity
抗原
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