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Mps1 抗体 (pThr676)

This anti-Mps1 antibody is a 兔 多克隆 antibody detecting Mps1 in ELISA 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN7224828
发货至: 中国

Quick Overview for Mps1 抗体 (pThr676) (ABIN7224828)

抗原

See all Mps1 (TTK) 抗体
Mps1 (TTK)

适用

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人, 小鼠

宿主

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克隆类型

  • 67
  • 9
多克隆

标记

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This Mps1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pThr676

    原理

    TTK (phospho Thr676) Polyclonal Antibody

    特异性

    Phospho-TTK (T676) Polyclonal Antibody detects endogenous levels of TTK protein only when phosphorylated at T676.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human TTK Phospho-Thr676

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Mps1 (TTK)

    别名

    TTK

    背景

    Rabbit Anti-TTK (phospho Thr676) Polyclonal Antibody,TTK, MPS1, MPS1L1, Dual specificity protein kinase TTK, Phosphotyrosine picked threonine-protein kinase, PYT,TTK (TTK protein kinase) encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.,Dual specificity protein kinase TTK

    基因ID

    7272

    UniProt

    P33981
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