mLC-2 (pThr17) 抗体
This 兔 多克隆 anti-not_set antibody specifically detects not_set in ELISA 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7219090
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for mLC-2 (pThr17) 抗体 (ABIN7219090)
抗原
mLC-2
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- pThr17
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原理
- MLC-2 (phospho Thr17/S18) Polyclonal Antibody
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特异性
- Phospho-MLC-2 (T17/S18) Polyclonal Antibody detects endogenous levels of MLC-2 protein only when phosphorylated at T17/S18.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human MLC-2 Phospho-Thr17/S18
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- mLC-2
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背景
- Rabbit Anti-MLC-2 (phospho Thr17/S18) Polyclonal Antibody,MYL12A, MLCB, MRLC3, RLC, Myosin regulatory light chain 12A, MLC-2B, Myosin RLC, Myosin regulatory light chain 2, nonsarcomeric, Myosin regulatory light chain MRLC3, MYL12B, MRLC2, MYLC2B, Myosin regulatory light chain 12B, MLC-2A, MLC-2, M,MYL12A encodes a nonsarcomeric myosin regulatory light chain. Myosin regulatory light chain 12A is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.,Myosin regulatory light chain 12A
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基因ID
- 10627
抗原
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