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MAP4K2 抗体 (AA 400-480)

This 兔 多克隆 anti-MAP4K2 antibody specifically detects MAP4K2 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7229498
发货至: 中国
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Quick Overview for MAP4K2 抗体 (AA 400-480) (ABIN7229498)

抗原

See all MAP4K2 抗体
MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))

适用

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宿主

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克隆类型

  • 50
多克隆

标记

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This MAP4K2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 400-480

    原理

    M4K2 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of M4K2 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human M4K2 protein at AA range: 400-480

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2))

    别名

    M4K2

    背景

    Rabbit Anti-M4K2 Polyclonal Antibody,Mitogen-activated protein kinase kinase kinase kinase 2, B lymphocyte serine/threonine-protein kinase, Germinal center kinase, GC kinase, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, MEKKK 2, Rab8-interacting protein,The protein encoded by MAP4K2 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2) is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1. Alternative splicing results in multiple transcript variants. MAP4K2 is a Protein Coding gene. Diseases associated with MAP4K2 include Cerebral Cavernous Malformations-2. Among its related pathways are TGF-Beta Pathway and MAPK signaling pathway.,M4K2

    分子量

    observerd band 90kDa

    基因ID

    5871

    UniProt

    Q12851
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