MCPH1 抗体 (AA 60-140)
Quick Overview for MCPH1 抗体 (AA 60-140) (ABIN7225086)
抗原
See all MCPH1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 60-140
-
原理
- Microcephalin Polyclonal Antibody
-
特异性
- Microcephalin Polyclonal Antibody detects endogenous levels of Microcephalin protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the N-terminal region of human Microcephalin at AA range: 60-140
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- MCPH1 (Microcephalin 1 (MCPH1))
-
别名
- Microcephalin
-
背景
- Rabbit Anti-Microcephalin Polyclonal Antibody,MCPH1, Microcephalin,MCPH1 (microcephalin 1) encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in MCPH1 have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.,Microcephalin
-
分子量
- observerd band 93kDa
-
基因ID
- 79648
-
UniProt
- Q8NEM0
-
途径
- Stem Cell Maintenance
抗原
-