Methylated Lysine 抗体
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北京 101111
Quick Overview for Methylated Lysine 抗体 (ABIN7206329)
抗原
适用
宿主
克隆类型
标记
应用范围
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原理
- Pan Methylated Lysine Monoclonal Antibody (Mix)
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特异性
- The antibody detects endogenous Pan Methylated Lysine protein.
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纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen
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免疫原
- Conjugated Protein
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亚型
- IgG1
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anti-Methylated Lysine (methylated) antibody
适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Methylated Lysine antibody适用: Various Species WB, IHC (p) 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-Methylated Lysine (pan) antibodyWB, ELISA, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Methylated Lysine (pan) antibodyWB, IHC 宿主: 小鼠 Monoclonal Mix unconjugated
anti-Methylated Lysine (pan) antibodyWB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000-1:2000), IHC-P (1:200-1:500).
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Methylated Lysine
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别名
- Pan Methylated Lysine
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物质类
- Chemical
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背景
- Mouse Anti-Pan Methylated Lysine Monoclonal Antibody (Mix),Lysine,Methylation of lysine residues is a common regulatory posttranslational modification (PTM) that results in the mono-, di-, or tri-methylation of lysine at ε-amine groups by protein lysine methyltransferases (PKMTs). Two PKMT groups are recognized based on structure and catalytic mechanism: class I methyltransferases or seven β strand enzymes, and SET domain-containing class V methyltransferases. Both use the methyl donor S-adenosyl-L-methionine to methylate histone and non-histone proteins. Class I methyltransferases methylate amino acids, DNA, and RNA. Six methyl-lysine-interacting protein families are distinguished based on binding domains: mBT, PHD finger, Tudor, PWWP, WD40 repeat, and chromodomains. Many of these display differential binding preferences based on lysine methylation state. KDM1 subfamily lysine demethylases catalyze demethylation of mono- and di-methyl lysines, while 2-oxoglutarate-dependent JmjC (KDM2-7) subfamily enzymes also modify tri-methyl lysine residues.,Lysine
抗原
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