Mesp2 抗体 (AA 220-300)
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Quick Overview for Mesp2 抗体 (AA 220-300) (ABIN7229648)
抗原
See all Mesp2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 220-300
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原理
- MESP2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of MESP2 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human MESP2 protein at AA range: 220-300
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Mesp2 (Mesoderm Posterior 2 Homolog (Mesp2))
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别名
- MESP2
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背景
- Rabbit Anti-MESP2 Polyclonal Antibody,Mesoderm posterior protein 2, Class C basic helix-loop-helix protein 6, bHLHc6,MESP2 (Mesoderm Posterior BHLH Transcription Factor 2) is a Protein Coding gene. Diseases associated with MESP2 include Spondylocostal Dysostosis 2, Autosomal Recessive and Spondylocostal Dysostosis, Autosomal Recessive. Among its related pathways are Cardiac Progenitor Differentiation and Gene regulatory network modelling somitogenesis. MESP2 encodes a member of the bHLH family of transcription factors and plays a key role in defining the rostrocaudal patterning of somites via interactions with multiple Notch signaling pathways. MESP2 is expressed in the anterior presomitic mesoderm and is downregulated immediately after the formation of segmented somites. MESP2 also plays a role in the formation of epithelial somitic mesoderm and cardiac mesoderm. Mutations in the MESP2 gene cause autosomal recessive spondylocostal dystosis 2 (SCD02).,MESP2
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分子量
- observerd band 43kDa
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基因ID
- 145873
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UniProt
- Q0VG99
抗原
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