MIA 抗体 (AA 60-140)
Our Local Distributor
北京 101111
Quick Overview for MIA 抗体 (AA 60-140) (ABIN7225216)
抗原
See all MIA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 60-140
-
原理
- MIA Polyclonal Antibody
-
特异性
- MIA Polyclonal Antibody detects endogenous levels of MIA protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the C-terminal region of human MIA at AA range: 60-140
-
亚型
- IgG
-
-
anti-Melanoma Inhibitory Activity (MIA) (Internal Region) antibody
Verified MIA 适用: 人 ELISA, IHC, WB 宿主: 山羊 Polyclonal unconjugated
anti-Melanoma Inhibitory Activity (MIA) antibodyMIA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Inhibitory Activity (MIA) (AA 87-124) antibodyMIA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Inhibitory Activity (MIA) antibodyMIA 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Inhibitory Activity (MIA) (AA 36-127) antibodyMIA 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Inhibitory Activity (MIA) (C-Term) antibodyMIA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Inhibitory Activity (MIA) (AA 1-131) antibodyMIA 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3A6 unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- MIA (Melanoma Inhibitory Activity (MIA))
-
别名
- MIA
-
背景
- Rabbit Anti-MIA Polyclonal Antibody,MIA, Melanoma-derived growth regulatory protein, Melanoma inhibitory activity protein,Tumorigenesis is a process that is mediated by a network of membrane, cytosolic and nuclear associated factors, which regulate proliferation and cell-matrix interaction through signaling cascades. The phenotype of malignant melanomas in vivo depends on the global expression of stimulatory or inhibitory factors generated in both the tumors cells and their environment. One example, Melanoma inhibitory activity (cartilage-derived retinoic acid-sensitive protein (CD-RAP), MIA) is a Src homology 3 (SH3)-like domain containing protein that is secreted from chondrocytes and malignant melanoma cells. MIA is translated as a 131-amino acid pro-form and processed into a mature 107-amino acid protein after cleavage of a secretion signal. MIA is expressed during chondrogenesis and in mature chondrocytes, suggesting that MIA is necessary for normal cartilage cell phenotype. MIA mRNA is present in carcinomas of the colon, ovary, kidney, and head/neck, and may represent a marker to monitor melanomic activity.,Melanoma-derived growth regulatory protein
-
基因ID
- 8190
-
UniProt
- Q16674
抗原
-
