MAGEB1 抗体 (AA 70-150)
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Quick Overview for MAGEB1 抗体 (AA 70-150) (ABIN7229524)
抗原
See all MAGEB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 70-150
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原理
- Rabbit Anti-MAGB1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of MAGB1 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human MAGB1 protein at AA range: 70-150
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- MAGEB1 (Melanoma Antigen Family B, 1 (MAGEB1))
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别名
- MAGB1
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背景
- Melanoma-associated antigen B1, Cancer/testis antigen 3.1, CT3.1, DSS-AHC critical interval MAGE superfamily 10, DAM10, MAGE-B1 antigen, MAGE-XP antigenMAGEB1 is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68 % sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. MAGEB1 is localized in the DSS (dosage-sensitive sex reversal) critical region, and expressed in testis and in a significant fraction of tumors of various histological types. MAGEB1 and other MAGEB members are clustered on chromosome Xp22-p21. Multiple alternatively spliced transcript variants encoding the same protein have been found for MAGEB1, however, the full length nature of some variants has not been defined. MAGEB4 is expressed in testis.
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分子量
- 38kD
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基因ID
- 4112
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UniProt
- P43366
抗原
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